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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX58
All Species:
31.82
Human Site:
T374
Identified Species:
70
UniProt:
Q96C10
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96C10
NP_077024.2
678
76613
T374
S
P
R
G
I
I
F
T
R
T
R
Q
S
A
H
Chimpanzee
Pan troglodytes
XP_001167051
678
76609
T374
S
S
R
G
I
I
F
T
R
T
R
Q
S
A
H
Rhesus Macaque
Macaca mulatta
XP_001108799
678
76729
T374
S
P
R
G
I
I
F
T
R
T
R
Q
S
A
H
Dog
Lupus familis
XP_850033
678
76952
T374
S
P
R
G
I
I
F
T
Q
T
R
Q
S
T
H
Cat
Felis silvestris
Mouse
Mus musculus
Q99J87
678
76708
T374
H
T
R
G
I
I
F
T
R
T
R
Q
T
A
S
Rat
Rattus norvegicus
NP_001092258
678
76894
T374
H
T
R
G
I
I
F
T
R
T
R
Q
T
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509166
910
103405
L617
N
P
E
S
R
T
I
L
F
V
K
T
R
A
L
Chicken
Gallus gallus
XP_422031
1285
144686
T983
E
P
R
G
I
I
F
T
K
T
R
Q
S
A
L
Frog
Xenopus laevis
NP_001085915
682
79226
T377
G
S
R
G
I
I
F
T
R
T
R
Q
S
T
H
Zebra Danio
Brachydanio rerio
XP_694124
738
84421
T429
K
A
R
G
I
I
F
T
Q
T
R
L
S
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176480
823
93488
S412
E
Y
A
E
N
E
D
S
S
S
I
I
F
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.8
84.6
N.A.
78.9
79.1
N.A.
26.9
23.7
51.1
38.8
N.A.
N.A.
N.A.
N.A.
28.6
Protein Similarity:
100
99.4
97.9
91.4
N.A.
87.6
87.7
N.A.
43.9
35.8
67.4
57.1
N.A.
N.A.
N.A.
N.A.
46.1
P-Site Identity:
100
93.3
100
86.6
N.A.
73.3
73.3
N.A.
13.3
80
80
66.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
100
93.3
N.A.
80
80
N.A.
26.6
86.6
80
73.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
0
0
0
0
0
0
73
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
19
0
10
10
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
82
0
10
0
0
0
10
0
0
% F
% Gly:
10
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% H
% Ile:
0
0
0
0
82
82
10
0
0
0
10
10
0
0
10
% I
% Lys:
10
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
19
0
0
73
0
0
0
% Q
% Arg:
0
0
82
0
10
0
0
0
55
0
82
0
10
0
0
% R
% Ser:
37
19
0
10
0
0
0
10
10
10
0
0
64
0
19
% S
% Thr:
0
19
0
0
0
10
0
82
0
82
0
10
19
28
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _